🩺 Aspadol 50 mg (Tapentadol) — Product Information
Generic Name: Tapentadol
Brand Name: Aspadol 50
Manufacturer: HAB Pharmaceuticals
Form: Immediate-Release Oral Tablet
Therapeutic Class: Centrally Acting Opioid Analgesic
✅ Indications
Aspadol 50 mg is used for the management of moderate to severe acute pain in adults, such as:
- Postoperative pain
- Musculoskeletal pain (e.g., back pain, arthritis)
- Injury-related pain
- Neuropathic pain
- Dental pain
⚙️ Mechanism of Action
Tapentadol acts through a dual mechanism:
- μ-Opioid Receptor Agonist: Alters the brain’s response to pain by binding to opioid receptors.
- Norepinephrine Reuptake Inhibitor (NRI): Enhances pain control by increasing norepinephrine levels in the nervous system.
This combination provides strong analgesia with a faster onset than many traditional opioids.
💊 Dosage & Administration
- Typical Dose: 50 mg every 4 to 6 hours as needed
- Maximum Daily Dose:
- Day 1: Do not exceed 700 mg
- Subsequent Days: Do not exceed 600 mg/day
- Route: Oral; swallow whole with water
- Food: Can be taken with or without food
- Do not chew, crush, or split the tablet
⚠️ Warnings & Precautions
- Addiction & Misuse: High potential for dependence and abuse
- Respiratory Depression: Risk increases with high doses or when combined with alcohol or CNS depressants
- CNS Effects: May cause dizziness, drowsiness, or impaired thinking
- Avoid Alcohol: Increases risk of severe side effects
- Pregnancy & Lactation: Not recommended—may cause neonatal withdrawal syndrome
- Driving/Machinery: Use caution until effects are known
❌ Side Effects
Common:
- Drowsiness
- Nausea & vomiting
- Dizziness
- Constipation
- Headache
Serious:
- Breathing difficulty
- Seizures
- Serotonin syndrome (confusion, agitation, high heart rate)
- Severe allergic reaction (rash, swelling, anaphylaxis)
Seek immediate medical help for any signs of serious side effects.
🔁 Missed Dose & Overdose
- Missed Dose: Skip and continue with the next dose. Do not double up.
- Overdose: Can cause life-threatening respiratory depression. Emergency treatment is required.
🔄 Alternatives / Substitutes
Other Tapentadol 50 mg brands available in India include:
- Tydol 50 (Sun Pharma)
- Vorth TP 50 (Integrace)
- Tapenta 50 (Zuventus)
- Duovolt 50 (Ipca Labs)
- Transdol 50 (Lupin)
Consult your healthcare provider before switching brands.
📌 Key Notes
- Use only under medical supervision
- Not suitable for long-term pain management
- Store below 30°C, away from moisture and light
- Keep out of reach of children